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THINGS THAT GO OUCH IN THE NIGHT
Page 3 of 3
by Howard Liss, MD and Donald Liss, MD

Pain unrelieved by rest

Sometimes, the lack of relief of symptoms at night should raise antennae. Statistically, although patients between age 20 and 50 need rarely undergo lumbosacral x-rays for low-back pain, one of the symptoms which should trigger suspicion is unremitting pain. If the patient describes pain which is positional, this generally points to a mechanical cause. Pain worsened by sitting, arising, or associated with flexion and rotation is often discogenic. Pain worsened by extension is often related to the facet joint. Pain exacerbated by walking is often associated with lumbar spinal stenosis. But ... pain which is unrelieved at night in any position may signify an underlying malignancy. This is especially true if there has been an associated loss of appetite, weight, or other constitutional symptoms such as change in bowel habits. At any rate, although most patients with this symptom do not have malignancy, this symptom should nevertheless trigger a more thorough diagnostic evaluation. One needs to have a high index of suspicion in these patients.

The other broad category of patients with unremitting pain are those patients with non-malignant but non-mechanical pain. Patients with visceral pain may present with complaints that seem musculoskeletal. A patient with perforated duodenal ulcer, for example, may present with acute mid-back pain which is severe and may be mistaken for muscular or spine pain. Only a high index of suspicion after thorough examination will lead to appropriate diagnostic testing.

Summary

In summary, most patients do not arrive with an easy answer to their diagnostic dilemmas. Patients have not read the textbook before arriving in the practitioner’s office. It is therefore imperative that every component of the medical history and physical examination be viewed discriminately and thought about judiciously. The effect of nighttime and bed rest on pain is an important example of this. The pattern of clinical presentation should affect our clinical impression and, therefore, our diagnostic workup; this in turn affects our treatment plan.


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